Organic KSM-66 Ashwagandha®

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Organic KSM-66 Ashwagandha®   

Found Takezō Energy, Focus, Rest, & Revive 

Takezō continuously seeks out the most effective ingredients on the planet.  Rest assured that KSM-66 is the most studied, bioavailable, and sustainably sourced Ashwagandha on the planet.   

Organic KSM-66® Ashwagandha is the industry leader in clinical trails and basic research investigating the effectiveness of ashwagandha ‡:(KSM-66 Infographics)

KSM-66 has been studied to test it’s effectiveness for:

 Why Takezo Chose KSM-66: 

  •  KSM-66 is the highest concentration, most bioavailable full-spectrum root extract on the market today, retaining all the natural constituents of the herb in the original balance. 
  • KSM-66 is the ashwagandha root extract with the most extensive set of research studies and clinical trials. 
  • KSM-66 has the highest percentage of withanolides of all branded root-only extracts available today. It has more than 5% concentration of withanolides as measured by HPLC. 
  • The production of KSM-66 has tight vertical integration for high quality and price advantage. KSM-66’s maker is the only ashwagandha manufacturer in the world with its own farms, production facilities, testing laboratories, research center and distribution. 
  • KSM-66 is the botanical with the highest number of certifications. KSM-66 and its manufacturing have gone through the most extensive inspections and safety assessments in our industry for the labels of GMP (USP, NSF, NPA-UL, WHO), 100% USDA Organic, Non-GMO (Non-GMO Project Verified), Gluten Free (by GFCO), BSCG-drug free, Kosher, Halal, HACCP and several others. 
  • KSM-66 has negligible levels of Withaferin A, a widely recognized cyto-toxic withanolide. 
  • KSM-66 is produced using a first-of-its-kind, unique extraction process, based on “Green Chemistry” principles, without using alcohol or any synthetic solvents. 
  • KSM-66 is GRAS Affirmed, Vegetarian, Safe and Shelf-stable. 

Check out the KSM-66 Ashwagandha Documentary

KSM-66 Organic Ashwagandha is widely regarded as the highest quality, highest concentration, full spectrum Ashwagandha root extract available on the market, standardized to the highest percentage of withanolides in the world.  Withanolides are the primary compounds responsible for the incredible benefits of this ayurvedic herb. 

What is Ashwagandha?

Ashwagandha (Withania somnifera Dunal) is the flagship herb of Ayurveda, the traditional system of medicine from India. This herb has been known for centuries but is only now experiencing major growth worldwide because of a burst of recent studies in pharmacology and medicine. Ashwagandha promotes balance in the body. It is an adaptogenic herb that helps the body successfully adapt to stressful conditions. Ashwagandha is one of the few herbs with significant effects on both psychological and physiological aspects of human functioning.

Both in independent clinical trials and in thousands of years of traditional use, the root is the part of the plant that is used predominantly, and not the aerials parts like the leaves. The use of the roots is on far better scientific foundation in terms of human clinical evidence and period of observation than the use of leaves. Experts argue for the use of the root only versus the leaves. Consistent with this, the canonical definition of ashwagandha in reference works like the pharmacopoeias is only on the root. These reference works are the United States Pharmacopoeia, the British Pharmacopoeia, the Indian Pharmacopoeia, the Ayurvedic Pharmacopoeia, Indian Materia Medica, the Health Canada monograph and the W.H.O. monograph. The leaf is in fact not even mentioned in any of them for therapeutic use. These reference works reflect the fact that expert consensus favors the root over the leaves.

Ashwagandha operates at the level of the overall body system by helping maintain balance in the substances and processes running in the human body. Ashwagandha is a small, woody shrub in the Solanaceae family that grows to about two feet in height. It can be found growing extensively in India as well as in a few parts of the Mediterranean and Africa. As a result of this wide ranging habitat, there are considerable morphological and chemo-typical variations in local species. However, the root phytoactives of both the wild and the cultivated species appear to be the same. Ashwagandha is referred to as the “Prince of Herbs” in Ayurveda because it has an impressively broad range of therapeutic effects. Such a broad range of effects arises perhaps because ashwagandha is one of the more complex herbs with many phytochemical constituents in it. While in the natural products marketplace, much of the discussion on ashwagandha is centered around the withanolides constituents or alkaloid constituents, Ayurvedic experts and doctors emphasize that there is much more to ashwagandha than just the withanolides. The synergistic effect from this diverse set of active constituents is believed to be responsible for the multiple therapeutic properties of ashwagandha. ~ KSM-66

What is KSM-66 & How Is It Made?

KSM-66 is Ixoreal’s ashwagandha extract, created via a process that took 14 years of R&D to develop and refine. KSM-66 is the best ashwagandha extract on the world market today in the sense that it is the highest concentration full-spectrum extract available today. A “full-spectrum” extract is an extract which maintains the balance of the various constituents as in the original herb, without over-representing any one constituent. The ashwagandha herb’s efficacy is believed to be derived from a complex blend of active constituents. All the constituents need to be present in their natural proportions, which is why it is important for an extract to be full-spectrum. However, producing a high concentration full-spectrum extract is technologically very challenging. Only Ixoreal has managed to create a process that surmounts these challenges, and that too only after many years of R&D. The Ixoreal science team sought to introduce to the world the true quintessence of ashwagandha with all its benefits. Convinced that the essence of the ashwagandha root could be extracted without losing its potency, the science team dedicated itself to learning the nuances of plant chemistry and did what no one was able to achieve until then. With `Green Chemistry` processing, they were able to holistically extract all the root essence while preserving its natural healing potency. This proved to be immensely successful. 

KSM-66’s extraction process entails pre-treating the ashwagandha roots with milk. For this reason, it contains milk constituents. Such pre-treatment is consistent with the process described by traditional ayurveda healers and texts. However, the traditional process does not scale up very well. Ixoreal has taken this traditional method and refined it greatly so that it produces high quality ashwagandha in a scalable manner, combining the traditional with the modern. Therein lies Ixoreal’s “secret sauce”, a highly proprietary process that took 14 years to develop and implement. The milk pre-treatment is important in our extraction process because this is in fact what leads to retention of both hydrophilic components and lipophilic components of the raw root, which in turn leads to a full-spectrum extract of such high-potency. ~ KSM-66

Quality Control:

Good Agricultural & Collection Practices (GACP) 

The ashwagandha root contains a variety of bio-active constituents. Different geographic locations determine the amounts and ratios of bio-active compounds in the ashwagandha root. Depending on soil conditions, the withanolide content in the ashwagandha root varies. The lower grade and older root stock is virtually useless and therapeutically, shows poor response. At Ixoreal, only high grade ashwagandha roots from the best geographic location are sourced. The herb requires well drained, sand loamy or light red soils with pH of 7.5-8.0. Ashwagandha is a late rainy season crop and requires relatively dry season. Areas receiving 650-750 mm rainfall are best suited for its cultivation. The state of Rajasthan in India is one of the most suited terrains known to grow the best quality ashwagandha in the world and that is where, our ashwagandha farms are located. The roots of ashwagandha are cultivated organically. No old root stock is used. Only special or High A-grade root pieces are used for the extraction. These roots are solid and bright, up to 7 centimeter, approximately and with a diameter of 1 to 1.5 centimeters. 

Current Good Manufacturing Practices (cGMP) 

Ixoreal stringently follows WHO and US-FDA guidelines on GMP. We invite our valued business partners for a tour of our state-of-the-art manufacturing unit, located at the Government of Andhra Pradesh (India) allocated Pharma zone. Our KSM-66 Ashwagandha processing is based on ‘Green Chemistry’ principles and ensures an effective overall approach to product quality control and risk management. We have set internationally approved standards and practices for product testing, manufacturing, storage, handling and distribution. Ixoreal firmly believes in offering a safe and effective product and therefore does not compromise on systems and documentation. All bulk and raw products are stored in quarantine before being subjected to KSM-66 Ashwagandha processing. To ensure KSM-66 Ashwagandha’s consistency and high quality and to prevent raw material and pre-finished material from being adulterated, contaminated or spoiled, Ixoreal, has established manufacturing controls at every stage. 

KSM-66 Ashwagandha processing is done in exclusively designed clean room systems. Our internal manufacturing controls provide documented proof that correct procedures are consistently followed at each step of processing and every time a batch extraction is made. Extensive controls cover the sanitation and hygiene of our facilities, personnel, utensils and machinery are strictly ensured. Controls are also in place for handling materials through out each step of the production process, such as work sheets, assuring consistency from batch-to-batch, easy monitoring and averting any chances of contamination and adulteration. 

Current Good Labratory Practices (cGLP):

Ixoreal subjects KSM-66 Ashwagandha to various internationally prescribed quality standards in its state-of-the art laboratory. All raw and finished material is inspected by the in-house quality control unit. Freshness labeling guidelines are followed. Trained and qualified personnel handle all the material, from raw stock to finished product. Based on client requirements, Ixoreal also offers to get its product tested in independent testing laboratories anywhere in the world. We welcome third party verification of our analytical reports. In short, Ixoreal Quality Control & Quality Assurance stages include: 

  • Quality on the farm 
  • Quality on receiving the raw material
  • In-house laboratory testing and segregation of raw material 
  • Organoleptic testing 
  • Moisture content analysis 
  • Microscopy and petri-grid analysis 
  • Microbiological testing 
  • Ash testing 
  • pH testing 
  • Aflatoxin testing 
  • Heavy metal analysis 
  • Pesticide analysis 
  • Bioactive Analysis 

Every sample and every dispatched batch is accompanied by certificate of analysis (COA) 

Good Packaging Practices (GPP)

Strict protocols are followed at every stage- from storing of raw herb to finished product. Precise labeling and hygienic handling are ensured. KSM-66 Ashwagandha packaging is done as per the Standard Exports Packaging policy. 

Social Responsibility:

A statement from the parent company of KSM-66 Ashwagandha: 

Ixoreal has several social impact projects because sustainability and corporate social responsibility are top priorities for the company. Because we operate our own farms  and work in such proximity with natural sources, we have a very real experiential sense that the sources are not limitless and that they need to be nurtured and replenished. Because our supply chain and production are fully vertically integrated and we do not want to subject to supply variation by sourcing from other ashwagandha growers, we have to make sure that our own ashwagandha farms will continue to supply ashwagandha far into the future. 

Sustainability is a top concern for us in the following important sense: Both in our day-to-day operations and our long-term strategic planning we are constantly mindful that anything we do today in our farms can have long-term impact on our supply and our company. In fact, we believe that our key resources are in our farms and in the workers that operate them.

Ixoreal Biomed is part of a family business group that has operated for over 80 years. Like many family businesses, we have expansive notion of “family, to include not just the owners but also the employees and their relatives and people living in the towns and communities that we occupy.

We discovered several decades ago that a company’s productivity is greatly increased if it is in happy, thriving communities. If the local community has social strife and unhappiness, it often works its ways into our own employees’ lives and affects productivity. For this reason and for the larger good, lxoreal is very enthusiastic about supporting human capital and traditional livelihoods in the areas we operate in. We operate social outreach and charity programs focusing on promoting health and education in the local communities by establishing schools, colleges, hospitals, community centers and parks.

  1. KSM-66 website 

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